Chondrosarcoma, a rare primary bone tumor with cartilaginous characteristics, accounts for about 20% of bone tumors and primarily requires surgical resection as current adjuvant treatments are ineffective. It typically originates in the arms, legs, or pelvis but can affect any cartilage-containing part of the body, sometimes arising de novo or from a benign bone tumor (enchondroma or osteochondroma).
Chondrosarcoma of Femur and Ilium:
This specimen shows the upper femur articulating with the pelvis and a malignantly-featured, lobulated, pale gray tumour with cavities, necrosis, and bleeding in the femur's neck, head, and most of the ilium. This tumour extends into surrounding tissue, indicating malignancy.
Chondrosarcoma of Scapula:
This specimen features an excised scapula with an 11cm irregular lobulated tumour. The tumour, identified as scapular chondrosarcoma, has infiltrated and replaced normal bone, displaying pleomorphic cells, mitotic figures, and cartilage formation.